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Cadherin E (Cadherin 1, E-Cadherin, L-CAM, Epithelial Cell Adhesion Molecule, Uvomorulin, CDH1)

Cadherin E (Cadherin 1, E-Cadherin, L-CAM, Epithelial Cell Adhesion Molecule, Uvomorulin, CDH1)

Cat no: C0108-25N3

Supplier: United States Biological
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E-cadherin (uvomorulin, cell- CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis. Applications: Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C0108-25N3
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in 10mM PBS, pH 7.2, 0.1% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by Protein A affinity chromatography.
Additional info: Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Orangutan (95%) due to sequence homology. Not yet tested in other species.

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