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Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD)

Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD)

Cat no: C0108-35F

Supplier: United States Biological
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N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin,, also known as Cadherin-2,encodes a 907aa protein that includes a 159aa signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C0108-35F
Reactivities: Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in 5mg BSA, 0.9mg sodium chloride, 0.2mg disodium hydrogen phosphate, 0.05mg thimerosal, 0.05mg sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes rat N-Cadherin.

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