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Calcitonin Receptor

Calcitonin Receptor

Cat no: C0115-19A

Supplier: United States Biological
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The calcitonin receptor is a seven transmembrane domain cell surface protein which is coupled to G protein messenger systems. Calcitonin receptor is expressed in kidney, central and peripheral nervous systems and in osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in fetal morphogenesis. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Cellular Localization: Integral membrane protein Positive Control: Kidney, cultered osteoclasts. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C0115-19A
Reactivities: Rat
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: 0.09% Sodium PBS
P type: Pab
Isotype: IgG
Purity: Purified
Alternative names: CRT, CTR, CT-R, CTR1, CALCR
References: 1. Tolcos, M. et al. (2003) Ontogeny of calcitonin receptor mRNA and protein in the developing central nervous system of the rat. J. Comp. Neurol. 456: 29 - 38. 2. Kovacs, C. S. et al. (2002) Calcitropic gene expression suggests a role for the intraplacental yolk sac in maternal-fetal calcium exchange. Am. J. Physiol. Endocrinol. Metab. 282: E721 - 732.
Additional info: Recognizes an epitope within the cytoplasmic domain that is common to both C1a and C1b rat isoforms

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