Home  >  Products  >  Calcium Transport Protein 2 (Calcium Transporter 2, CaT2, Epithelial Calcium Channel 1, ECAC 1, ECAC1, ECaC, Osm-9-like TRP Channel 3, OTRPC 3, OTRPC3, Transient Receptor Potential Cation Channel Subfamily V Member 5, TRPV 5, TRPV5)

Calcium Transport Protein 2 (Calcium Transporter 2, CaT2, Epithelial Calcium Channel 1, ECAC 1, ECAC1, ECaC, Osm-9-like TRP Channel 3, OTRPC 3, OTRPC3, Transient Receptor Potential Cation Channel Subfamily V Member 5, TRPV 5, TRPV5)

Cat no: C0122-02


Supplier: United States Biological
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This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq] Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 1-3ug/ml Band at ~85kD. Optimal dilutions to be determined by the researcher. Positive Control: Human Pancreas lysates Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C0122-02
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. van der Eerden BC, Hoenderop JG, de Vries TJ, et al. The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17507-12. Epub 2005 Nov 16. PMID: 16291808
Additional info: Recognizes human TRPV5 at ~85kD. Species sequence homology: mouse and rat.

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