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Calreticulin (CALR, SSA, Sicca Syndrome Antigen A, Ro, Autoantigen Ro)

Cat no: C1036-02Z


Supplier: United States Biological
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Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to the endoplasmic reticulum (ER), but has also been detected in the nucleus and nuclear envelop. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus (1-3). CRT
Catalogue number: C1036-02Z
Reactivities: Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Guinea Pig, Non-Human Primate, Porcine, Sheep
Hosts: Rabbit
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid.
P type: Pab
Isotype: IgG
Purity: Serum.
References: 1. Johnson S., et al. (2001) Trends Cell Biol 11: 122-129. 2. Smith M.J., et al. (1989) EMBO J. 8: 3581-3586. 3. Ellgaard L., et al. (2001) Curr Opin Cell Biol. 13: 431- 437. 4. Krause K.H., and Michalak M. (1997) Cell. 88: 439- 443. 5. Nash P.D., et al. (1994) Mol Cell Biochem. 135: 71-78. 6. Heal R., and McGivan J. (1998) Biochem J. 329: 389- 394. 7. Lucero H.A., et al. (1998) J Biol Chem. 273: 9857- 9863. 8. Tanaka S., et al. (2000) J Biol Chem. 275: 10388-10393. 9. Yoon G.S., et al. (2000) Cancer Res. 60: 1117-1120. 10. Antoniou A.N., et al. (2002) Immunology 106: 182-189. 11. Wada I., et al. (1997) EMBO J. 16: 5420-5432. 12. Laguerre D.B., et al. (1998) J Vir. 72: 4940-4949.
Additional info: Recognizes human calreticulin. Species Crossreactivity: mouse, rat, bovine, canine, chicken, guinea pig, monkey, porcine, hamster, sheep.

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