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Calreticulin, Recombinant, Human (His) (CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60)

Calreticulin, Recombinant, Human (His) (CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60)

Cat no: 044624

Supplier: United States Biological
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Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis. Sequence: Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 044624
Size: 10ug
Form: Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Purity: >90% (SDS-PAGE)
Alternative names: CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60

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