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Calsequestrin-2, aa20-399, Recombinant, Human (CASQ2, Calsequestrin Cardiac Muscle Isoform, FLJ26321, FLJ93514, PDIB2)

Cat no: C1036-08

Calsequestrin-2, aa20-399, Recombinant, Human (CASQ2, Calsequestrin Cardiac Muscle Isoform, FLJ26321, FLJ93514, PDIB2)

Calsequestrin2 is a calcium-binding protein of the sarcoplasmic reticulum. The protein helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. It also helps sarcoplasmic reticulum store an amazing amount of calcium ions. Recombinant Calsequestrin2 protein was expressed in E. coli.\n\nSource: \nRecombinant corresponding to aa20-399 of human Calsequestrin-2 6x His tagged expressed in E. coli.\n\nAA Sequence:\nMRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEEG LNFPTYDGKD RVVSLSEKNF KQVLKKYDLL CLYYHEPVSS DKVTQKQFQL KEIVLELVAQ VLEHKAIGFV MVDAKKEAKL AKKLGFDEEG SLYILKGDRT IEFDGEFAAD VLVEFLLDLI EDPVEIISSK LEVQAFERIE DYIKLIGFFK SEDSEYYKAF EEAAEHFQPY IKFFATFDKG VAKKLSLKMN EVDFYEPFMD EPIAIPNKPY TEEELVEFVK EHQRPTLRRL RPEEMFETWE DDLNGIHIVA FAEKSDPDGY EFLEILKQVA RDNTDNPDLS ILWIDPDDFP LLVAYWEKTF KIDLFRPQIG VVNVTDADSV WMEIPDDDDL PTAEELEDWI EDVLSGKINT EDDDEDDDDD DNSDEEDNDD SDDDDDE\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C1036-08

Size

100ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris HCl, pH 8.0, 0.1M NaCl, 1mM DTT, 20% glycerol.

Purity

~95% by SDS-PAGE. Purified by using conventional chromatography techniques.

References

1. Wang S,, et al. (1998) Nat. Struct. Biol.. 5(6):476

Alternative Names

Calsequestrin 2 (Cardiac Muscle)

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