Home  >  Products  >  Cannabinoid Receptor 1 (CANN6, CB R, CB1, CB1A, CB1K5, Central cannabinoid receptor isoform a, Central cannabinoid receptor isoform b, CNR)
Cannabinoid Receptor 1 (CANN6, CB R, CB1, CB1A, CB1K5, Central cannabinoid receptor isoform a, Central cannabinoid receptor isoform b, CNR)

Cannabinoid Receptor 1 (CANN6, CB R, CB1, CB1A, CB1K5, Central cannabinoid receptor isoform a, Central cannabinoid receptor isoform b, CNR)

Cat no: C1075-70T

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina. Cellular Localization: Integral membrane protein Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C1075-70T
Reactivities: Human, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Western Blot
Size: 100ul
Form: PBS, 50% glycerol, 1 mg/ml BSA and 0.05% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: CANN6, CB R, CB1, CB1A, CB1K5, Central cannabinoid receptor isoform a, Central cannabinoid receptor isoform b, CNR
References: Tsou K et al. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411 (1998). Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J Neurophysiol 78:43-50 (1997).
Additional info: Detects CB1 from human and rat tissues as well as transfected rat CB1. Species Crossreactivity: Crossreacts with Human and Rat .Not yet tested in other species.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave