Home  >  Products  >  Caper (RNPC2, RNA-binding region containing protein 2, Coactivator of activating protein-1 and estrogen receptors, HCC1, Hepatocellular carcinoma protein 1, Splicing factor CC1.3, Splicing factor CC1.4)
Caper (RNPC2, RNA-binding region containing protein 2, Coactivator of activating protein-1 and estrogen receptors, HCC1, Hepatocellular carcinoma protein 1, Splicing factor CC1.3, Splicing factor CC1.4)

Caper (RNPC2, RNA-binding region containing protein 2, Coactivator of activating protein-1 and estrogen receptors, HCC1, Hepatocellular carcinoma protein 1, Splicing factor CC1.3, Splicing factor CC1.4)

Cat no: C1077-10B

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Heterogeneous nuclear ribonucleoproteins (hnRNP) bind to nascent RNA polymerase II transcripts and are involved in transcript-specific packaging as well as alternative splicing of pre-mRNAs. hnRNPs also appear to influence mRNA metabolism and transport. In vivo, the M proteins bind to mRNA, and in vitro they bind avidly to poly(G) and poly(U) homopolymers. Four different isoforms of hnRNP are produced by alternative splicing: M1, M2, M3, and M4. Ongoing studies have theorized that hnRNPs may cause certain genetic diseases such as myotonic dystrophy, which is the most common form of adult muscular dystrophy. The identification of hnRNPs may therefore be important to determining the cause and cure for genetic diseases. Transcriptional coactivators either bridge transcription factors and the components of the basal transcription apparatus and/or remodel the chromatin structures. CAPER (coactivator of activating protein-1 (AP-1) and estrogen receptors (ERs)) may represent a selective transcriptional coactivator molecule that plays a pivotal role for the function of AP-1 and ERs in vivo in conjunction with the general coactivator ASC-2. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C1077-10B
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: RNPC2, RNA-binding region containing protein 2, Coactivator of activating protein-1 and estrogen receptors, HCC1, Hepatocellular carcinoma protein 1, Splicing factor CC1.3, Splicing factor CC1.4
Additional info: This antibody is specific for human Caper. Species Crossreactivity: reacts with human protein. Other species have not been tested. Reactivity with mouse Caper is likely owing to conservation between the mouse sequence and the peptide used for this antibody production.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave