

Supplier:
Alomone Labs Ltd.Cat no: C-125
Capsaicin
Vanilloid receptor 1 (VR1), also known as TRPV1, is a nonselective cation channel that is activated by heat and acid, as well as vanilloids.
Capsaicin is a TRPV1 agonist, which acts directly on TRPV1. Being small and hydrophobic, capsaicin crosses the plasma membrane readily to reach its intracellular ligand-binding site on TRPV1, leading to channel activation and cation permeation.
Capsaicin acts directly on TRPV1, with half-maximal effective concentration of 711.9пїЅnM in Xenopus oocytes and 0.29 μM in HEK293 cells.
Ion Channel Modulators; TRP Channel Modulators.
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SPECIFICATIONS
Catalog Number
C-125
Size
1 g
Purity
>98%
Concentration
0.1-10 uM
Shipping Temp
Room Temperature
Molecular Weight
305.4 da
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