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CAPZA2 pAb

CAPZA2 pAb

Cat no: BS6543

Supplier: Bioworld Technology, Inc.
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The F-Actin family of capping proteins includes CapZ-(alpha)1, CapZ-(alpha)2, CapZ-(alpha)3 and CapZ-(beta)3, all of which function in a calcium-dependent manner and bind to the fast growing barbed end of Actin filaments, thereby blocking protein exchange at these ends. The F-Actin capping protein complex is a heterodimer consisting of (alpha) and (beta) subunits that caps the barbed ends of Actin filaments and nucleates the polymerization of Actin monomers, yet does not sever Actin filaments. CapZ-(alpha)1, also known as F-Actin-capping protein subunit alpha-1, is a 286 amino acid subunit of the heterodimer that forms the F-Actin capping protein complex. CapZ-(alpha)1 also has been shown to bind S-100 (beta) chain, a signaling molecule involved in the calcium-sensitive assembly of intermediate filaments that has been linked to Alzheimer's disease.
Catalogue number: BS6543
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P47755
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human CAPZA2.
Species: CAPZA2 pAb detects endogenous levels of CAPZA2 protein.
Molecular weight: ~ 33 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CAPPA2; Capping protein (actin filament) muscle Z line; alpha 2; CapZ alpha 2; CapZ alpha-2; CAPZ; CAPZA2; CAZA2; F actin capping protein subunit alpha 2; F-actin-capping protein subunit alpha-2;
Additional info: For research use only, not for use in diagnostic procedure.

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