Carcinoembryonic antigen (CEA) is also known as CD66e and is a member of the immunoglobulin supergene family that is mainly expressed on epithelial cells. CD66e may play a role in cancer cells metastasis, and has been used clinically as a tumor marker for early detection of disease.
Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (paraffin): 1:100-1:200. Requires protein digestion pre-treatment of paraffin sections e.g. pronase.
Immunohistochemistry: frozen sections
Optimal dilutions to be determined by the researcher.
Immunohistochemistry Positive Control Tissue:
Adenocarcinoma of colon
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.