Home  >  Products  >  Carcinoembryonic Antigen (CEA, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66e, CD66e Antigen, DKFZp781M2392, Meconium Antigen 100)

Carcinoembryonic Antigen (CEA, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66e, CD66e Antigen, DKFZp781M2392, Meconium Antigen 100)

Cat no: C1300-01K


Supplier: United States Biological
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CEA is a glycoprotein constituent of embryonic endodermal epithelium. It is a complex molecule of 200kD. Specific for CEA, the antibody may be used in studying and monitoring primary and secondary tumors of the gastrointestinal tract. Strongly stains tumor cells present in cancerous colon tissue. Only very weak staining of normal tissue observed. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: Frozen Immunohistochemistry (Paraffin): 1:10-1:40 Does not require protein digestion pre-treatment of paraffin sections. Does not require antigen retrieval using heat treatment prior to staining of sections. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C1300-01K
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in PBS, 0.09% sodium azide, 1% BSA.
P type: Mab
Isotype: IgG1
Purity: Supernatant
References: 1. Gold, P. and Freedman, S.O. (1965) Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. J. Exp. Med. 121: 439-462. 2. Herberman, R.B. (1977) Immunologic tests in diagnosis of cancer. J. Clin. Pathol. 68: 688-698. 3. Freireich, E.J. (1978) Oncology. J.A.M.A. 239: 517-518. 4. Ghosh, A.K. et al. (1987) Immunocytological staining reactions of anti-carcinoembryonic antigen, Ca, and anti-human milk fat globule monoclonal antibodies on benign and malignant exfoliated mesothelial cells. J. Clin. Pathol. 40: 1424-1427. 5. MacDonald, F. et al. (1988) Expression of CEA, CA125, CA19-9 and human milk fat globule membrane antigen in ovarian tumours. J. Clin. Pathol. 41: 260-264. 6. Seth, J. et al. (1988) Carcinoembryonic antigen. Lancet 18: 1399. 7. De Potter, C.R. et al. (1988) CEA and HMFG in hyperplastic and malignant lesions of the breast. Pathol. Res. Pract. 183: 271-276. 8. Tron, V. et al. (1987) Carcinoembryonic antigen and milk-fat globule protein staining of malignant mesothelioma and adenocarcinoma of the lung. Arch. Pathol. Lab. Med. 111: 291-293.
Additional info: Recognizes the human Carcinoembryonic Antigen (CEA). Does not crossreact with NCA (Non-specific cross-reacting antigen).

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