caspase-10 Antibody

Cat no: 252225

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

Caspase-10 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Caspase-10 is recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner, and participates in the granzyme B apoptotic pathways. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Defects in caspase-10 are a cause of familial non-Hodgkin lymphoma (NHL). NHL is a cancer that starts in cells of the lymph system, which is part of the body's immune system. NHLs can occur at any age and are often marked by enlarged lymph nodes, fever and weight loss.

Catalogue number:	252225
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q92851
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-10.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Caspase-10; CASP-10; ICE-like apoptotic protease 4; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; CASP10; MCH4