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Caspase 12 (P99) Peptide

Caspase 12 (P99) Peptide

Cat no: BS3542P

Supplier: Bioworld Technology, Inc.
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Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, caspase-14, and caspase-5/caspase-12. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 (also designated TY or ICErelIII) can cleave its own precursor, an activity that requires the cysteine 245 residue. The mouse homolog of caspase-5 is designated caspase-12. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon and stomach, indicating that caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer.
Catalogue number: BS3542P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q6UXS9
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Caspase 12 (P99). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Inactive caspase-12; CASP-12; UNQ9415/PRO34398; CASP12; Caspase12
Additional info: This peptide can be used with studies using BS3542 Caspase 12 (P99) pAb.

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