Caspase-3 Antibody

Cat no: 250573

Supplier: ABBIOTEC

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Description
Additional Information

Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9.

Catalogue number:	250573
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P42574
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Yana protein; SREBP cleavage activity 1; SCA-1; CASP3; CPP32