Caspase-3 Antibody

Cat no: 251937

Supplier: ABBIOTEC

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Description
Additional Information

Caspase-3 (CASP-3) is involved in the activation of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase-3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, leucine zipper domain and the membrane attachment domain. Caspase-3 cleaves and activates caspase-6, -7 and -9, and is involved in the cleavage of huntingtin.

Catalogue number:	251937
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P42574
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Caspase-3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.2, with 0.02% sodium azide, 0.5% BSA. Antibody was antigen affinity purified.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Caspase-3; CASP-3; Apopain; Cystein protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; CASP3; CPP32