Catalogue number: | C2087-24A2 |
Reactivities: | Human, Mouse |
Hosts: | Rabbit |
Applications: | Immunohistochemistry, Western Blot |
Size: | 100ug |
Form: | Supplied as a liquid in PBS, 0.02% sodium azide |
P type: | Pab |
Isotype: | IgG |
Purity: | Purified by Immunoaffinity chromatography |
References: | 1. Martinon F. and Tschopp J. (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-574. 2. Kuida K., Lippke J.A., Ku G., et al. (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267:2000-2003. 3. Gracie J.A., Robertson S.E. and McInnes I.B. (2003) Interleukin-18. J. Leukoc. Biol. 73:213-224. 4. Kamens J., Paskind M., Hugunin M. et al. (1995) Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. J. Biol. Chem. 270:15250-6. 5. Hitomi J., Katayama T., Eguchi Y. et al. (2004) Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J. Cell Biol. 165:347-356. |
Additional info: | Recognizes human Caspase-4. Depending on cell lines or tissues used, other cleavage products may be observed. Species Crossreactivity: mouse |