Caspase-7 (CASP-7, Apoptotic Protease Mch-3, CMH-1, ICE-like Apoptotic Protease 3, ICE-LAP3, CASP7, MCH3)

Cat no: C2087-29C8

Supplier: United States Biological

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Along with caspase-3 and -6, Caspase-7 is a member of the apoptotic executioner or effector caspases . Caspase-7 is cleaved by granzyme B and caspase-3,-6,-8, and -9. It is suggested that caspase-7 may be an important intrcellular effector of granzyme B-mediated apoptosis and cytotoxic T lymphocytes-induced cell killing in vivo. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2087-29C8
Reactivities:	Human, Mouse
Hosts:	Rat
Applications:	Western Blot
Size:	25ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type:	Mab
Isotype:	IgG2a
Purity:	Purified by immunoaffinity chromatography.
References:	1. Long H et al. 1998. Cell 94:491. 2. Duan H et al. 1996. J. Biol. Chem. 271:1621. 3. Nicholson D. 1999 Cell Death and Differentiation 6:1028.
Additional info:	Recognizes human Caspase-7. Species Crossreactivity: mouse.

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Caspase-7 (CASP-7, Apoptotic Protease Mch-3, CMH-1, ICE-like Apoptotic Protease 3, ICE-LAP3, CASP7, MCH3)

Cat no: C2087-29C8

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