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CASQ2 (Calsequestrin-2, Calsequestrin, Cardiac Muscle Isoform)

Cat no: C1036-07


Supplier: United States Biological
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The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C1036-07
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Mab
Isotype: IgG2b,k
Purity: Purified.
References: 1.A novel mouse model of X-linked cardiac hypertrophy. Leatherbury L, Yu Q, Chatterjee B, Walker DL, Yu Z, Tian X, Lo CW.Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2701-11. Epub 2008 Apr 18.
Additional info: Recognizes human CASQ2.

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