Cathepsin D Antibody

Cat no: 251720

Supplier: ABBIOTEC

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Description
Additional Information

Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Cathepsin D consists of a light chain and a heavy chain. Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10), also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material. This results in seizures, dementia, visual loss, and/or cerebral atrophy.

Catalogue number:	251720
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P07339
Antigen:	Human liver cathepsin D.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a
Clonality:	CP-D13
Additional info:	Cathepsin D; CTSD; CPSD