Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Cat no: C2097-91T

Supplier: United States Biological

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Cav1 is a 21kD scaffolding protein which is the main component of the caveolae plasma membranes found in most cell types. Two isoforms (alpha and beta) are encoded by a single transcript from this gene. Cav1 is highly expressed in terminally differentiated or quiescent cells, suggesting a possible role for Cav1 as a negative regulator of cell proliferation. Cav1 has been implicated in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis and functions as a

Catalogue number:	C2097-91T
Reactivities:	Human
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris-saline, pH7.3, 0.02% sodium azide, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Williams, T.M. and Lisanti, M.P. (2005) Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am. J. Physiol. Cell. Physiol. 288: 494-506. 2. Liu, P. et al. (2002) Multiple functions of caveolin-1. J. Biol. Chem. 277: 41295-41298.
Additional info:	Recognizes human CAVEOLIN 1. Species sequence homology: rat, mouse, canine and porcine.

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Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Cat no: C2097-91T

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