Home  >  Products  >  Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21)
Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21)

Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21)

Cat no: C2097-98A

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin-embedded sections): 1:500 Western Blot: 1ug/ml. Detects caveolin 3 from rat heart homogenate at ~21kD. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2097-98A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 1mg/ml BSA., 0.05% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21
References: 1. Tang Z et al. Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem 271:2255-61 (1996).
Additional info: Recognizes human caveolin-3. Does not react with caveolin-1 or -2. Species Crossreactivity: rat and mouse

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave