Caveolin proteins are components of caveolae plasma membranes found in most cell types. Caveolin-3 is the muscle-specific form of the caveolin protein family whose members are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules within the caveolae membranes. Mutations in caveolin-3 have been isolated which interfere with caveolin-3 oligomerization and disrupt caveolae formation resulting in limb-girdle muscular dystrophy.
Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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