CBX5 Polyclonal Antibody

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SPECIFICATIONS

Price

323.00 USD

Catalog Number

CAC07297

Size

100 micro g

Applications

IHC, WB

Hosts

Rabbit

Conjugates

Unconj

Purity

Protein G purified, >95%

Target

CBX5

Clonality

Polyclonal

Storage Temp

Aliquot and store at -20 degrees C. Minimize freezing and thawing.

Research Area

For research use only. Not for diagnostic procedures.

Shipping Temp

Blue ice

Additional Info

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Alternative Names

Chromobox protein homolog 5,Antigen p25,Heterochromatin protein 1 homolog alpha, HP1 alpha,CBX5,HP1A