CCR-3 Antibody

Cat no: 251536

Supplier: ABBIOTEC

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Description
Additional Information

C-C chemokine receptor type 3 (CCR-3) is a receptor for C-C type chemokine. CCR-3 binds to eota, Xenopus/Amphibian,in, eota, Xenopus/Amphibian,in-3,Mouse,CP-3,Mouse,CP-4, RANTES and MIP-1 delta. The activation of CCR-3 subsequently transduces a signal by increasing the intracellular calcium ions level. CCR-3 is an alternative coreceptor with CD4 for HIV-1 infection. Overe, Xenopus/Amphibian,pression of CCR-3 together with its ligands appears to be a characteristic of ulcerative colitis (UC). The production of CCR-3 ligands by human colonic epithelial cells suggests further that the epithelium can play a role in modulating pathological T cell-mediated mucosal inflammation.

Catalogue number:	251536
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P51677
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CCR-3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	CCR-3; C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR3; CKR3; Eosinophil eota, Xenopus/Amphibian,in receptor; CD193; CMKBR3