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CCR6 (Chemokine Receptor 6, CC-CCR-6)

CCR6 (Chemokine Receptor 6, CC-CCR-6)

Cat no: C2099-70J

Supplier: United States Biological
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Cellular Localization: Integral membrane protein Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2099-70J
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography.
Alternative names: Chemokine Receptor 6, CC-CCR-6
References: Wells TN et al. Definition, function and pathophysiological significance of chemokine receptors. Trends Pharmacol Sci 19:376-80 (1998). Greaves DR et al. CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells. J Exp Med 186:837-44 (1997). Baba M et al. Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC. J Biol Chem 272:14893-8 (1997).
Additional info: Human CCR6 reacts with CCR6 transfected cells and not with the parent cell line by flow cytometry. The antibody shows no crossreactivity with CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CXCR1, CXCR2, CXCR3, CXCR4 and STRL33 transfected cells. Species Crossreactivity: Crossreacts with Human.Not yet tested in other species.

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