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CD103

Cat no: C2445-63E

CD103

CD103 is the integrin alphaE subunit which usually forms a heterodimer with the integrin beta7 subunit. It is expressed on intraepithelial lymphocytes and 1-2% of peripheral blood lymphocytes. CD103 binds E-cadherin on epithelial cells. This interaction may be of importance in the homing and retention of CD103+ lymphocytes in the intestinal epithelium.1-4\n\nApplications:\n

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SPECIFICATIONS

Catalog Number

C2445-63E

Size

100ug

Applications

FC, IHC, IP

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in phosphate buffered saline, 0.1% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Kishimoto, T., A.E.G. von dern Borne, S.M. Goyert, D.Y. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw, T.A. Springer, K. Sugamura, and H. Zola, eds. 1998. Leukocyte Typing VI: White Cell Differentiation Antigens, Academic Press, New York.\n2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD103 Section, Academic Press, New York, p. 379.\n3. Shaw, S.K., K.L. Cepek, E.A. Murphy, G.J. Russell, M.B. Brenner, and C.M. Parker 1994. J. Biol. Chem. 269:6016.\n4. Shaw, S.K., and M.B. Brenner. 1995. Semin. Immunol. 7:335.

Additional Info

Recognizes human CD103.

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