Home  >  Products  >  CD103 (CD103 Antigen, HML-1 Antigen, Human Mucosal Lymphocyte Antigen 1, Huminae, Integrin alpha E, ITGAE, Integrin alpha IEL, MGC141996, Mucosal Lymphocyte 1 Antigen, Mucosal Lymphocyte Antigen 1)

CD103 (CD103 Antigen, HML-1 Antigen, Human Mucosal Lymphocyte Antigen 1, Huminae, Integrin alpha E, ITGAE, Integrin alpha IEL, MGC141996, Mucosal Lymphocyte 1 Antigen, Mucosal Lymphocyte Antigen 1)

Cat no: C2445-64E


Supplier: United States Biological
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CD103 is the integrin alphaE subunit which usually forms a heterodimer with the integrin beta7 subunit. It is expressed on intraepithelial lymphocytes and 1-2% of peripheral blood lymphocytes. CD103 binds E-cadherin on epithelial cells. This interaction may be of importance in the homing and retention of CD103+ lymphocytes in the intestinal epithelium.1-4 Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2445-64E
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Flenghi, L. et al. (1990) LF61: a new monoclonal antibody directed against a trimeric molecule (150kD, 125kD, 105kD) associated with hairy cell leukaemia. Br. J. Haem. 76:451-459. 2. Falini, B. et al. (1990) Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients. Br. J. Haem. 76:460-468.
Additional info: Recognizes human CD103.

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