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CD104 (Integrin beta4)

Cat no: C2446-01C

CD104 (Integrin beta4)

Human beta4 integrin is also known as CD104. It is a 205kD glycoprotein. It associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumor cell lines.\n\nApplications: \nSuitable for use in Immunohistochemistry and Immunopreciptiation. Other applications have not been tested.\n\nRecommended Dilutions:\nImmunoprecipitation: Labeled cell extract 5ul of serum is sufficient to precipitate a6b4 from 1-2x10e6 cells. In some cases immunoprecipitation from 35S methionine labeled cells originates two bands of 95 and 55kD of unknown origin in addition to the 200kD and 140kD bands corresponding to b4 and a6.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2446-01C

Size

100ul

Applications

IHC, IP

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid, 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. J. Cell. Biol. (1990). 111:1593

Additional Info

Recognizes human b4 integrin. The epitope recognized is on the cytoplasmic domain of the protein and is thus intracellular. No crossreactivity to other integrin b subunits. Species Crossreactivity: rat and mouse

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