Catalogue number: |
C2448-02G |
Reactivities: |
Human, Non-Human Primate |
Hosts: |
Mouse |
Applications: |
Flow Cytometry |
Size: |
50ug |
Form: |
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. |
P type: |
Mab |
Isotype: |
IgG1 |
Purity: |
Purified by Protein G affinity chromatography. |
Alternative names: |
CD117 antigen, C-Kit, Mast/stem cell growth factor receptor precursor, PBT, Proto-oncogene tyrosine-protein kinase Kit, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
References: |
Yoshino N et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim 49:97-110 (2000). Broudy VC et al. Analysis of c-kit receptor dimerization by fluorescence resonance energy transfer. Blood 91:898-906 (1998). |
Additional info: |
This antibody recognizes the human c-Kit. c-Kit is expressed by some haematopoietic stem cells (approx. 70% of CD34 +ve cells in normal bone marrow are c-Kit +ve), by some acute myeloid leukaemias and by mast cells.This antibody is non-neutralising. Species Crossreactivity: Crossreacts with Human and Cynomolgus Monkey. Not yet tested in other species. |