CD11a (HI111) Antibody

Cat no: 250944

Supplier: ABBIOTEC

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Description
Additional Information

The CD11a (HI111) antibody recognizes the 180-kDa integrin ? chain associated with CD18, the 95-kDa integrin (B)2, which form a heterodimer glycoprotein called the lymphocyte function antigen-1 (LFA-1, CD11a/CD18). Leukocytes e, Xenopus/Amphibian,press four CD11/CD18 integrins which include a common (B)2 subunit and distinctive ? chains. Besides CD11a/CD18, the other three integrins are known as CD11b/CD18, CD11c/CD18 and CD11d/CD18. LFA-1 is e, Xenopus/Amphibian,pressed on all leukocytes and is responsible for adhesion between leukocytes during immune response and transmigration of leukocytes across endothelium. The ligands for CD11a/CD18 are intercellular adhesion molecules CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). Patients bearing mutated CD18 genes do not e, Xenopus/Amphibian,press cell membrane LFA-1, a condition known as leukocyte adhesion deficiency 1 (LAD-1).

Catalogue number:	250944
Reactivities:	Human
Applications:	Flow Cytometry, Immunohistochemistry
Size:	0.1 mg
Accession:	P20701
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG1
Clonality:	HI111
Additional info:	Integrin alpha-L; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD11 antigen-like family member A; CD11a antigen; ITGAL; CD11A