Home  >  Products  >  CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)
CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

Cat no: C2262-51E

Supplier: United States Biological
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CD11b, also known as the integrin aM subunit, forms a heterodimer with CD18, the integrin b2 subunit. The heterodimer is known as integrin Mac-1. This CD11b/CD18 heterodimer binds the complement fragment iC3b, fibrinogen, factor X, CD23, neutrophil inhibitory factor, and several other ligands. In binding ICAM-1, the CD11b/CD18 heterodimer mediates neutrophil and monocyte adhesion to endothelium. Applications: Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 1ml ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2262-51E
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 1ml
Form: Supplied as a lyophilized powder in sodium azide. Reconstitute with 1ml ddH2O.
P type: Mab
Isotype: IgG3
Purity: Purified
Alternative names: Integrin, alpha M (Complement Component 3 Receptor 3 Subunit)
Additional info: Recognizes human CD11b/CD18 monocytes.

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