CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor) (PE, Cy5)

Applications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: Neat-1:5; 10ul labels 10e6 cells in 100ul\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\n\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

C2262-37G

Size

100Tests

Applications

FC

Hosts

Rat

Reactivities

Hum, Mouse, Rabbit

Form

Supplied as a liquid in PBS, sucrose, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE)-Cy5.

P Type

Mab

Purity

Purified

Isotype

IgG2b

References

1. Springer, T. et al. (1978) Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8:539-551, 2. Springer, T. et al. (1979) Mac-1: a macrophage differentiation antigen identified by a monoclonal antibody. Eur. J. Immunol. 9:301-306, 3. Beller, D.I. et al. (1982) Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor J. Exp. Med. 156:1000-1009, 4. Whiteland, J.L. et al. (1995) Immunohistochemical detection of T cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J. Histochem. Cytochem. 43:313-320, 5. Klingel, K. et al. (2003) Beta2-microglobulin-associated regulation of interferon-gamma and virus-specific immunoglobulin G confer resistance against the development of chronic coxsackievirus myocarditis. Am. J. Pathol. 162(5):1709-1720, 6. Welt, F.G. et al. (2000) Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries. Arterioscler Thromb Vasc Biol. 20: 2553-2558.

Additional Info

Recognizes mouse CD11b. Species Crossreactivity: human, rabbit.

Alternative Names

Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor