Home  >  Products  >  CD11c (Integrin alpha-X, CD11 Antigen-like Family Member C, Leu M5, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, ITGAX)
CD11c (Integrin alpha-X, CD11 Antigen-like Family Member C, Leu M5, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, ITGAX)

CD11c (Integrin alpha-X, CD11 Antigen-like Family Member C, Leu M5, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, ITGAX)

Cat no: C2262-65X

Supplier: United States Biological
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CD11c is a 145-150kD type I transmembrane glycoprotein also known as integrin ax, and CR4. CD11c non-covalently associates with integrin B2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)2ug/10e5 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2262-65X
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Sadhu, C., et al. 2008. J. Immunoass. Immunoch. 29:42. 2. Rezzonico, R., et al. 2001. Blood. 97:2932. 3. Sadhu, C., et al. 2007. J. Leukoc. Biol. 81:1395. 4. Yoshino, N., et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC) 5. Petty, H. 1996. Immunol. Today 17:209. 6. Springer, T. 1994. Cell 76:301. 7. Ihanus E., et al. 2007. Blood. 109:802-810.
Additional info: Recognizes human CD11c.

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