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CD13 (Aminopeptidase N, AP-N, hAPN, Alanyl Aminopeptidase, Aminopeptidase M, AP-M, Microsomal Aminopeptidase, Myeloid Plasma Membrane Glycoprotein CD13, gp150, ANPEP, APN, PEPN)

CD13 (Aminopeptidase N, AP-N, hAPN, Alanyl Aminopeptidase, Aminopeptidase M, AP-M, Microsomal Aminopeptidase, Myeloid Plasma Membrane Glycoprotein CD13, gp150, ANPEP, APN, PEPN)

Cat no: C2264-12E

Supplier: United States Biological
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CD13 is a 150-170kD type II transmembrane glycoprotein also known as aminopeptidase N, APN, and gp150. This zinc metallopeptidase as a homodimer is expressed on granulocytes, myeloid progenitors, endothelial cells, epithelial cells and subset of granular lymphoid cells. It is not expressed on platelets or erythrocytes. CD13 is thought to be involved in the metabolism of many regulatory peptides and functions in antigen processing and the cleavage of chemokines such as MIP-1. CD13 serves as the cellular receptor for Coronavirus. Applications: Suitable for use in Flow Cytometry, Blocking and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)2ug/10e5 cells in 100ul Immunohistochemistry: acetone-fixed, frozen tissue sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2264-12E
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Knapp, W., et al. 1989. Leucocyte Typing IV. Oxford University Press. New York. 2. Saiki, I., et al. 1993. Int J Cancer. 54:137. 3. Rosenzwajg, M., et al. 2000. Blood 95:453. 4. Kawase, M., et al. 2008. J Virol. 5. Shipp, M., et al. 1993. Blood 82:1052. 6. Larsen, S., et al. 1996. J. Exp. Med. 184:183.
Additional info: Recognizes human CD13. Species Crossreactivity: chimpanzee.

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