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CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

Cat no: 044648

Supplier: United States Biological
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CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice. Sequence: The cysteine-rich region of human CD137 (aa 1-186) is fused to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.
Catalogue number: 044648
Size: 50ug
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity: >95% (SDS-PAGE)
Alternative names: 4-1BB, TNFRSF9
Additional info: Binds to human CD137L (4-1BBL).

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