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CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

Cat no: 044648

CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.\n\nSequence:\nThe cysteine-rich region of human CD137 (aa 1-186) is fused to the Fc portion of human IgG1.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nStable for at least 6 months after receipt when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044648

Size

50ug

Form

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.

Purity

>95% (SDS-PAGE)

Additional Info

Binds to human CD137L (4-1BBL).

Alternative Names

4-1BB, TNFRSF9

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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