CD14 (HI221) Antibody

Cat no: 251003

Supplier: ABBIOTEC

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Description
Additional Information

The CD14 (HI221) antibody recognizes a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein, which is found on cells of myelomonocytic lineage including monocytes (strongly), granulocytes (weakly) and also on most tissue macrophages. CD14 antigen is also present on reticular dendritic cells, some Langerhans cells, and B lymphocytes (weakly), but is absent from T lymphocytes, NK cells, erythrocytes and platelets. CD14 functions as a high affinity receptor for the comple, Xenopus/Amphibian, of lipopolysaccharide (LPS-endoto, Xenopus/Amphibian,in) and LPS-binding protein (LBP), and is the major receptor involved in the lethal response to both endoto, Xenopus/Amphibian,in and Gram-negative bacteria. In addition to membrane CD14, soluble form of CD14 can be detected in serum and tissue culture supernatants of cells transfected with CD14.

Catalogue number:	251003
Reactivities:	Human
Applications:	Flow Cytometry
Size:	2 ml
Accession:	P08571, NP_000582
Format:	Each vial contains 2 ml IgM (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by hydro, Xenopus/Amphibian,yapatite chromatography.
P type:	Mouse Monoclonal Antibody, FITC-conjugated Antibody
Isotype:	mouse IgM
Clonality:	HI221
Additional info:	Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; Monocyte differentiation antigen CD14, urinary form; Monocyte fiferentiation antigen CD14,Mouse,embrane-bound form; CD14