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CD153 (CD30 Ligand, CD30LG, CD30-L, MGC138144, Tumor Necrosis Factor (Ligand) Superfamily Member 8, TNFSF8)

CD153 (CD30 Ligand, CD30LG, CD30-L, MGC138144, Tumor Necrosis Factor (Ligand) Superfamily Member 8, TNFSF8)

Cat no: C2548-84J1

Supplier: United States Biological
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CD153 is a 39-40kD type II membrane glycoprotein, also known as CD30 ligand or CD30L. This TNF superfamily member is expressed on activated T cells. CD153 has been reported to stimulate B-cell proliferation, antigen-specific antibody production, polyclonal immunoglobulin secretion, and T cell activation and proliferation. This antibody inhibits binding of CD153 to CD30. Applications: Suitable for use in Flow Cytometry and Functional Assays. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2548-84J1
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.4. No preservatives added.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography. Endotoxin Level (same/less than)0.01EU/ug
References: 1. Shimozako, O. et al. (1999) Expression of CD30 ligand (CD153) on murine activated T cells. Biochem. Biophys. Res. Commun. 256: 519-526.
Additional info: Recognizes mouse CD153.

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