Home  >  Products  >  CD154 (CD40 Ligand, Cd40l, CD40-L, Cd40lg, sCD40L, HIGM1, IGM, IMD3, Ly62, Ly-62, T-BAM, T-cell Antigen Gp39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, Tnfsf5) (Azide Free)

CD154 (CD40 Ligand, Cd40l, CD40-L, Cd40lg, sCD40L, HIGM1, IGM, IMD3, Ly62, Ly-62, T-BAM, T-cell Antigen Gp39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, Tnfsf5) (Azide Free)

Cat no: C2548-84YF


Supplier: United States Biological
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CD154, which is the CD40 ligand (CD40L) and is also known as gp39, a transmembrane glycoprotein. CD154 is expressed by activated T-cells, and serves an important function in T-APC cognate interaction through binding to CD40 on B cells, monocytes/macrophages and dendritic cells. This antibody inhibits the binding of gp39 to CD40 as well as B cell activation. Applications: Suitable for use in Functional Assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2548-84YF
Reactivities: Mouse
Size: 100ug
Form: Supplied as a liquid in PBS. No preservative added (Azide free).
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. Gordon, J. and Pound, J.D. (2000) Fortifying B cells with CD154: an engaging tale of many hues. Immunol. 100: 269-280.
Additional info: Recognizes mouse CD154.

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