CD16 alpha Antibody

Cat no: 250164

Supplier: ABBIOTEC

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Description
Additional Information

This antibody recognizes a polymorphism variant of CD16 alpha antigen, which is a low affinity receptor for aggregated IgG (Fc gamma receptor III). The receptor e, Xenopus/Amphibian,ists in two distinct forms: a glycosyl phosphatidyl inositol (GPI) form (Fc gamma RIIIB), and an integral membrane protein (Fc gamma RIIIA). In humans, the transmembrane form is e, Xenopus/Amphibian,pressed on NK cells and macrophages whereas the GPI-linked form is e, Xenopus/Amphibian,pressed on granulocytes. This antibody binds both forms but binds poorly to NK cells from donors not carrying the polymorphism. The antibody can be used for detecting CD16 in flow cytometry, immunoprecipitation, western blot and blocks ligand binding.

Catalogue number:	250164
Reactivities:	Human
Applications:	Flow Cytometry, Western Blot
Size:	0.1 mg
Accession:	P08637, NP_000560
Antigen:	?
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG1
Clonality:	MEM154
Additional info:	Low affinity immunoglobulin gamma Fc region receptor III-A; IgG Fc receptor III-2; Fc-gamma RIII-alpha; Fc-gamma RIIIa; FcRIIIa; Fc-gamma RIII; FcRIII; FcR-10; CD16a antigen; FCGR3A; CD16A; FCG3; FCGR3; IGFR3