Home  >  Products  >  CD163 (Scavenger Receptor Cysteine-rich Type 1 Protein M130, Hemoglobin Scavenger Receptor, M130)
CD163 (Scavenger Receptor Cysteine-rich Type 1 Protein M130, Hemoglobin Scavenger Receptor, M130)

CD163 (Scavenger Receptor Cysteine-rich Type 1 Protein M130, Hemoglobin Scavenger Receptor, M130)

Cat no: C2548-90G5

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
CD163, a member of the group B scavenger receptor cysteine-rich superfamily, is a 134kD (non-reduced)/155kD (reduced) glycoprotein primarily expressed on macrophages, Kuffer cells, monocytes, subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP) resulting in soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammation diseases. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)2ug/10e5 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2548-90G5
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Pulford, K., et al. 1992. Immunology 75:588. (IP) 2. Law, S.K., et al. 1993. Eur. J. Immunol. 23:2320. 3. Madsen, M., et al. 2004. J. Biol. Chem. 279:51561. 4. Kim, W.K., et al. 2006. Am. J. Pathol. 168:822. (FC) 5. Roth, J., et al. 1994, Transolantation. 57:127. 6. Van den Heuvel, MM., et al.1999, J. Leukoc Biol. 66:858. 7. Sulahian, T. H., et al. 2000, Cytokines 12:1312. 8. Fabriek, BO., et al. 2007, J. Neuroimmunol. 187:179.
Additional info: Recognizes human CD163.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave