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CD166 (Activated Leukocyte Cell Adhesion Molecule, CD166 Antigen, ALCAM, MEMD)

CD166 (Activated Leukocyte Cell Adhesion Molecule, CD166 Antigen, ALCAM, MEMD)

Cat no: C2548-90P2

Supplier: United States Biological
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CD166, also known as the CD6 ligand or the Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a 100-105kD transmembrane glycoprotein. It belongs to the Ig superfamily of proteins and expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently CD166 has also been used as a potential cancer stem cell marker. The antibody reacts with human activated leukocyte cell adhesion molecule (ALCAM). Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.5ug/10e5 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2548-90P2
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Aruffo A., et al. 1997. Immunol Today. 18(10):498. 2. Patel DD., et al. 1995. J Exp Med. 181:2213. 3. Bowen MA., et al. 1995. J Exp Med. 181:1563. 4. Horst D., et al. 2009. Cancer Invest. 22:1.
Additional info: Recognizes human CD166.

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