CD168 Peptide

Cat no: BS5651P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan that regulates cell adhesion and migration. HA effects are mediated through two receptors, CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM, also designated intracellular hyaluronic acid binding protein (IHABP) and CD168, is a matrix receptor, which is linked to the plasma membrane by a GPI anchor and regulates cell motility. RHAMM expression is upregulated in malignant lymphoid tissues and is subsequently implicated in tumor progression and metastasis formation, as well as signal transduction. Although still unclear, RHAMM is thought to exist as several isoforms ranging in size. A variant isoform, designated v4, is a protein that when over-expressed, is thought to be the cause of transformation and metastasis formation in fibroblasts.

Catalogue number:	BS5651P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O75330
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CD168. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Hyaluronan mediated motility receptor; Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; HMMR; IHABP; RHAMM
Additional info:	This peptide can be used with studies using BS5651 CD168 pAb.

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CD168 Peptide

Cat no: BS5651P

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