Home  >  Products  >  CD177 (CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA 2a, HNA2a, HNA-2a, NB1, NB1 Glycoprotein, NB1 gP, Polycythemia Rubra Vera 1, PRV 1, PRV1, PRV-1)

CD177 (CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA 2a, HNA2a, HNA-2a, NB1, NB1 Glycoprotein, NB1 gP, Polycythemia Rubra Vera 1, PRV 1, PRV1, PRV-1)

Cat no: C2548-90YB


Supplier: United States Biological
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The neutrophil NB1 antigen is expressed by 97% of the caucasian population. Antibodies against CD17 can be involved in neonatal alloimmune neutropenia (NAN). Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2548-90YB
Reactivities: Human, Non-Human Primate
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by protein G affinity chromatography.
Alternative names: CD177 Molecule
References: 1. Caruccio, L. et al. (2003) Expression of human neutrophil antigen-2a (NB1) is increased in pregnancy. Transfusion. 43: 357 - 363. 2. Kissel, K. et al. (2002) Molecular basis of NB1 (HNA-2a, CD177) deficiency. Blood. 99: 4231 - 4233.
Additional info: Recognizes human CD177 (neutrophil glycoprotein NB1). Species Crossreactivity: Rhesus Monkey.

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