Home  >  Products  >  CD178 (Tumor Necrosis Factor Ligand Superfamily Member 6, Apoptosis Antigen Ligand, APTL, CD95 Ligand, CD95-L, Fas Antigen Ligand, Fas Ligand, FASLG, APT1LG1, CD95L, FASL, TNFSF6) (Biotin)
CD178 (Tumor Necrosis Factor Ligand Superfamily Member 6, Apoptosis Antigen Ligand, APTL, CD95 Ligand, CD95-L, Fas Antigen Ligand, Fas Ligand, FASLG, APT1LG1, CD95L, FASL, TNFSF6) (Biotin)

CD178 (Tumor Necrosis Factor Ligand Superfamily Member 6, Apoptosis Antigen Ligand, APTL, CD95 Ligand, CD95-L, Fas Antigen Ligand, Fas Ligand, FASLG, APT1LG1, CD95L, FASL, TNFSF6) (Biotin)

Cat no: C2548-91Q

Supplier: United States Biological
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CD178 is a 40kD member of the TNF/NGF superfamily also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. Cell surface CD178 is expressed on activated T cells and in testis and eye. CD178 is upregulated in activated T cells upon TCR re-engagement and has been shown to induce autocrine and paracrine T cell death. The MFL4 antibody recognizes CD178 in a wide array of mouse strains and has been reported to block CD178/CD95 induced apoptosis. The MFL4 antibody is cross-reactive with rat FasL. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.25ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2548-91Q
Reactivities: Mouse, Rat
Applications: Flow Cytometry
Conjugates: Biotin
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
P type: Mab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Trinit
Additional info: Recognizes mouse CD178. Species Crossreactivity: rat.

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