CD18 Integrin beta-2 Antibody

Cat no: 251165

Supplier: ABBIOTEC

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Description
Additional Information

CD18 Integrin beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. CD18 Integrin beta-2 is a receptor for the iC3b fragment of the third complement component and for fibrinogen. CD18 Integrin beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, binds P1 and P2 peptides of fibrinogen gamma chain, and is also a receptor for factor , Xenopus/Amphibian,. Defects in CD18 Integrin beta-2 are the cause of leukocyte adhesion deficiency type 1 (LAD1). LAD1 patients have recurrent bacterial infections and their leukocytes are deficient in a wide range of adhesion-dependent functions.

Catalogue number:	251165
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P05107
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD18 Integrin beta-2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; MFI7; Integrin (B)2; Integrin-(B)2