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CD18 (Integrin beta-2, Cell Surface Adhesion Glycoproteins LFA-1/CR3/p150,95 Subunit beta, Complement Receptor C3 Subunit beta, ITGB2, MFI7)

CD18 (Integrin beta-2, Cell Surface Adhesion Glycoproteins LFA-1/CR3/p150,95 Subunit beta, Complement Receptor C3 Subunit beta, ITGB2, MFI7)

Cat no: C2269-08F

Supplier: United States Biological
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CD18 is a 90-95 kD type I transmembrane protein also known as integrin b2 subunit, LFA-1 b subunit, and b2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated a chains function in adhesion and signaling in hematopoietic cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2269-08F
Reactivities: Human, Porcine
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Schlossman, S., et al. 1995. Leucocyte Typing V. Oxford University Press. New York. 2. Kishimoto, T., et al. 1997. Leucocyte Typing VI. Garland Press. London. 3. Van Epps, D.E., et al. 1989. J. Immunol. 143:3207. 4. Meerschaert, J., et al. 1994. J. Immunol. 152:1915. 5. Sithu, S.D., et al. 2007. J. Biol. Chem. doi:10.1074/jbc.M611273200. 6. Nakayama, H., et al. 2008. J. Leukocyte Biol. 83:728. 7. Carmona, G., et al. 2008. Blood 111:2640. 8. Tran, DQ., et al. 2009. J. Immunol. 182:2929. 9. Anderson, D., et al. 1987. Annu. Rev. Med. 38:175. 10. Springer, T., 1994. Cell 76:301.
Additional info: Recognizes human CD18. Species Crossreactivity: porcine.

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