Home  >  Products  >  CD180 (CD180 Antigen, Lymphocyte Antigen 64, Ly64, Lymphocyte Antigen 78, Ly78, MGC126233, MGC126234, Radioprotective 105kD Protein, RP105) (FITC)
CD180 (CD180 Antigen, Lymphocyte Antigen 64, Ly64, Lymphocyte Antigen 78, Ly78, MGC126233, MGC126234, Radioprotective 105kD Protein, RP105) (FITC)

CD180 (CD180 Antigen, Lymphocyte Antigen 64, Ly64, Lymphocyte Antigen 78, Ly78, MGC126233, MGC126234, Radioprotective 105kD Protein, RP105) (FITC)

Cat no: C2548-93D1

Supplier: United States Biological
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CD180 is a type 1 transmembrane protein, which belongs to the toll-like receptor family. CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. Cross linking of CD180 with clone MHR73 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule CD80. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: Neat; 10ul labels 10e6 cells in 100ul. Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2548-93D1
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: CD180 Molecule, F630107B15, Radioprotective 105kD Protein
References: 1. Miura, Y. et al. (1998). RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood. 92:2815-2822.
Additional info: Recognizes human CD180.

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