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CD19 (B-lymphocyte Antigen CD19, B-lymphocyte Surface Antigen B4, Differentiation Antigen CD19, T-cell Surface Antigen Leu-12)

CD19 (B-lymphocyte Antigen CD19, B-lymphocyte Surface Antigen B4, Differentiation Antigen CD19, T-cell Surface Antigen Leu-12)

Cat no: C2269-82X

Supplier: United States Biological
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CD19 is a 95 kD type I transmembrane glycoprotein is also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2269-82X
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Schlossman, S., et al. 1995. Leucocyte Typing V. Oxford University Press. New York. 2. Knapp, W., et al. 1989. Leucocyte Typing IV. Oxford University Press. New York. 3. Bradbury, L., et al. 1993. J. Immunol. 151:2915. 4. Joseph, A., et al. 2010. J. Virol. 84:6645. 5. Wang, X., et al. 2010. Haematologica. 95:884. (FC) 6. Walker, J.D., et al. 2009. J. Immunol. 182:1548. (Block) 7. Yoshino, N., et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC) 8. Tedder, T., et al. 1994. Immunol. Today 15:437. 9. Bradbury, L., et al. 1993. J. Immunol. 151:2915.
Additional info: Recognizes human CD19. Species Crossreactivity: chimpanzee, baboon.

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